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Today's pharmaceutical market very often requires rotating load sterilization autoclaves.

These units are based on conventional sterilization principles (saturated steam or counterpressure methods, such as superheated water spray and steam+air mixtures), but the load is rotated throughout the process at an adjustable speed (1 to 5 rpm), intermittently, and (if required) in alternating directions.

This rotation may be used for various purposes, but the three most frequent ones are:

• To maintain the stability and homogeneity of suspensions or emulsions that, mainly due to the sterilization temperature, would tend to separate out.

• To provide the best possible testing of ampoule tightness with fast post-sterilization vacuum. It is know that this method provides its maximum effectiveness when the "open" defects of the ampoules are below the level of the solution. Load rotation is the ideal method to achieve this condition, regardless of the location of the defects on the ampoules.

• To sterilize heat-sensitive products at a high temperature for a very short time. Obviously, in order to achieve this result effectively, the product heating/cooling rates must be very high and uniform. Rotation, by stirring the product, indeed facilitates the penetration/ removal of the heat into/from the product, especially if the product is dense and viscous.

Naturally the production of this type of autoclave requires highly refined design and construction technology, especially when the loads have a considerable mass.

Our company has specialized in the manufacture of these machines by also drawing on its decades of experience in the construction of autoclaves with rotating drums for the complete treatment of stoppers and similar devices.

We are at the full disposal of our Clients for further technical information, references and quotations.

 







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