Fedegari at 2016 PDA Universe of Pre-filled Syringes and Injection Devices

14 October 2016

Are you joining the next 2016 PDA Universe of Pre-filled Syringes and Injection Devices, in California? Come to learn more about our case study: An innovative way to thermally sterilize Hyaluronic acid PFS.

From October 16-18, our R&D experts would be glad to answer your questions and discuss about challenges on PFS sterilization.

We look forward to seeing you at the Hyatt Regency Huntington Beach Resort and Spa, Huntington Beach, CA!

 

Case study:  An innovative way to thermally sterilize Hyaluronic acid PFS.

In collaboration with IBSA International.

Abstract:

Several reports on degradation of HA involving microwaves, UV or γ-rays have been published. Rheological studies also show that HA solutions degrade at high temperature: viscosity of the solutions decreases in time as a function of temperature. Therefore, its thermal sterilization treatment always represents a challenge. An optimized moist heat sterilization cycle can minimize product degradation (and change of molecular weight) maintaining the required viscosity for the specific application.

 

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